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Feelings and Cancer. Indomethacin Interactions. About About Drugs. Iroko Pharmaceuticals, LLC. Call your doctor for medical advice about side effects. Not all possible interactions are listed in this medication guide. May mask signs of infection or fever. Use the arrow keys to move through the suggestions. See also: Nonsteroidal anti-inflammatory drug. Resources for News Media. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. The awkward case of 'his or her'. For instance, indometacin inhibits both cyclooxygenase-1 and cyclooxygenase-2which then inhibits the production of prostaglandins in the stomach and intestines responsible for maintaining the mucous lining of the gastrointestinal tract. Injectable: This medication is available in an injectable form to be given directly into a vein IV by a healthcare professional. Store at room temperature away from moisture and heat. Choices for Care. It should always be taken with food. This Indocin does not have an English version. Comparative IIndocin safety of traditional nonsteroidal anti-inflammatory drugs. This medicine may also be used to treat painful shoulder caused by bursitis or tendinitis. What side effects can this medication cause? Tell your doctor if you are pregnant or plan to become pregnant while using indomethacin. The post-hoc sensitivity analyses, which were performed without the eight patients from the centre that was closed, did not change the efficacy results of the study substantially and therefore do not affect any conclusions drawn. Do not take two doses of indomethacin at the same time. Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Questions to Ask About Cancer. If you will be using indomethacin suppositories, also tell your doctor if you have or have ever had proctitis inflammation of the rectum or have or have recently had rectal Indocn. Before taking indomethacin, tell your Imdocin and pharmacist if you are allergic Idocin indomethacin, aspirin or other NSAIDs such as ibuprofen Advil, Motrin and naproxen Aleve, Naprosynany other medications, or any of the inactive ingredients in indomethacin capsules, suspension, extended release capsules, or suppositories. Jung, H. Indocin Drug Class Back to Top. The patient's and physician's global assessment of response to treatment, and physician's assessment of tenderness, swelling and erythema of the study joint were also assessed. This medicine can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Injectable: This medication is available in an injectable form to be given directly into a vein IV by a healthcare professional. Indomethacin slide 15 of 17, Indomethacin. Legislative History. First, a little about yourself Male Female. It works by stopping the body's production of a substance that causes pain, fever, and inflammation. What other information should I know? Transfer of a Grant. Indocin and Pregnancy Back to Top. Lumiracoxib is a novel selective COX-2 inhibitor that has been reported to be effective in treating acute pain, such as after dental surgery [ 11 ], arthroplasty [ 12 ] and sprains and strains [ 13 ], and in treating chronic pain associated with osteoarthritis OA [ 14 ].

Indocin - something is

Female Cancers of Childhood National. Show More. Indomethacin may also be used for others Indocin bad in this condition guide. Thus indometacin users have an unbalanced risk of illness toxicity. Tell your flack if any of these people are able or do not go away: teenager sewage vomiting diarrhea constipation difficulty of the dose constant crying of the need to empty the bowel postural in the ears Some side effects can be serious. Interactive Indovin. Manufacturer Back to Top. Instead, the best way Indocin dispose of your medication is through a medicine take-back program. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Talking about Your Advanced Cancer. Moderate to severe rheumatoid arthritis, osteoarthritis, ankylosing spondylitis.
(Active Ingredient: Indomethacin)
Indocin, a nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
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    Indocin is used for treating moderate to severe rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is used to treat gout or certain types of bursitis and tendonitis. It may also be used for other conditions as determined by your doctor. Indocin is an NSAID. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.


    Use Indocin as directed by your doctor! Check the label on the medicine for exact dosing instructions.

    • Take Indocin by mouth with food. This may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor if you have persistent stomach upset.
    • Take Indocin with a full glass of water (8 oz/240 mL) as directed by your doctor.
    • If you miss a dose of Indocin and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

    Ask your health care provider any questions you may have about how to use Indocin .


    Store Indocin at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Indocin out of the reach of children.


    Active Ingredient: Indomethacin.

  • Do NOT use Indocin if:

    • you are allergic to any ingredient in Indocin
    • you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or an NSAID (eg, ibuprofen, celecoxib)
    • you have recently had or will be having bypass heart surgery
    • you are taking diflunisal, another NSAID (eg, ibuprofen), or triamterene
    • you are in the last 3 months of pregnancy

    Contact your doctor or health care provider right away if any of these apply to you.

    Some medical conditions may interact with Indocin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

    • if you are pregnant, planning to become pregnant, or are breast-feeding
    • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
    • if you have allergies to medicines, foods, or other substances
    • if you have a history of kidney or liver disease, diabetes, or stomach or bowel problems (eg, bleeding, perforation, ulcers, inflammation)
    • if you have a history of swelling or fluid buildup, depression, mental or mood problems, seizures, Parkinson disease, asthma, growths in the nose (nasal polyps), or mouth inflammation
    • if you have high blood pressure, a blood disorder, bleeding or clotting problems, heart problems (eg, heart failure), or blood vessel disease, or if you are at risk for any of these diseases
    • if you have poor health, dehydration or low fluid volume, low blood sodium levels, or high blood potassium levels, you drink alcohol, or you have a history of alcohol abuse.

    Some medicines may interact with Indocin. Tell your health care provider if you are taking any other medicines, especially any of the following:

    • Anticoagulants (eg, warfarin), corticosteroids (eg, prednisone), diflunisal, heparin, other NSAIDs (eg, ibuprofen), salicylates (eg, aspirin), or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because the risk of stomach bleeding may be increased
    • Potassium-sparing diuretics (eg, spironolactone, triamterene) because the risk of kidney problems or increased blood potassium levels may be increased
    • Cyclophosphamide because low blood sodium levels may occur
    • Probenecid because it may increase the risk of Indocin 's side effects
    • Cyclosporine, digoxin, lithium, methotrexate, quinolones (eg, ciprofloxacin), or sulfonylureas (eg, glipizide) because the risk of their side effects may be increased by Indocin
    • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin receptor blockers (eg, losartan), beta-blockers (eg, propranolol), or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Indocin.

    This may not be a complete list of all interactions that may occur. Ask your health care provider if Indocin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

    Important safety information:

    • Indocin may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Indocin with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
    • Serious stomach ulcers or bleeding can occur with the use of Indocin. Taking it in high doses or for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Indocin with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you develop severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling.
    • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
    • Indocin is an NSAID. Before you start taking any new medicine, read the ingredients. If it also has an NSAID (eg, ibuprofen) in it, check with your doctor. If you are not sure, check with your doctor or pharmacist.
    • Do not take aspirin while you are using Indocin unless your doctor tells you to.
    • Indocin may interfere with certain lab tests. Be sure your doctor and lab personnel know that you take Indocin .
    • Lab tests, including kidney function, complete blood cell counts, and blood pressure, may be done to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
    • Use Indocin with caution in the elderly; they may be more sensitive to its effects, including stomach bleeding, kidney problems, confusion, or mental changes.
    • Indocin should be used with extreme caution in children younger 15 year; safety and effectiveness in these children have not been confirmed.
    • Pregnancy and breast-feeding: Indocin may harm the fetus. Do not use it during the last 3 months of pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Indocin while you are pregnant. Indocin is found in breast milk. Do not breast-feed while you are taking Indocin .
  • All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist or become bothersome:

    Constipation; diarrhea; dizziness; drowsiness; gas; headache; heartburn; nausea; stomach upset.

    Seek medical attention right away if any of these severe side effects occur:

    Severe allergic reactions (rash; hives; itching; trouble breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine; bloody or black, tarry stools; change in the amount of urine produced; chest pain; confusion; dark urine; depression; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; mental or mood changes; numbness of an arm or leg; one-sided weakness; rectal bleeding; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe headache or dizziness; severe or persistent stomach pain or nausea; severe vomiting; shortness of breath; sudden or unexplained weight gain; swelling of hands, legs, or feet; unusual bruising or bleeding; unusual joint or muscle pain; unusual tiredness or weakness; unusual vaginal bleeding; vision or speech changes; vomit that looks like coffee grounds; yellowing of the skin or eyes.

    This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.